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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21A
All Species:
17.58
Human Site:
S549
Identified Species:
48.33
UniProt:
Q641Q2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q641Q2
NP_001005751.1
1341
147184
S549
E
D
S
E
D
L
F
S
S
Q
S
A
S
K
L
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
S637
E
D
S
E
D
L
F
S
S
Q
S
A
S
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
S460
D
D
E
D
E
E
V
S
S
V
Q
S
D
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
S543
E
D
S
E
D
L
F
S
S
Q
S
S
S
K
P
Rat
Rattus norvegicus
Q80X08
1328
145131
S541
E
D
S
E
D
L
F
S
S
Q
S
S
S
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
E536
F
S
D
E
E
D
S
E
D
L
F
S
S
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
T644
Q
K
S
K
N
I
E
T
G
E
K
Q
H
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
Q823
P
V
P
Q
T
K
N
Q
S
E
S
E
K
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
65.9
N.A.
73.5
72.7
N.A.
N.A.
55.4
N.A.
21.7
N.A.
20.4
N.A.
N.A.
24.1
Protein Similarity:
100
92.6
N.A.
70.6
N.A.
80.5
80
N.A.
N.A.
68.7
N.A.
26.2
N.A.
36.6
N.A.
N.A.
36.2
P-Site Identity:
100
93.3
N.A.
20
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
0
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
N.A.
46.6
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
0
N.A.
60
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
56
12
12
45
12
0
0
12
0
0
0
12
12
0
% D
% Glu:
45
0
12
56
23
12
12
12
0
23
0
12
0
0
12
% E
% Phe:
12
0
0
0
0
0
45
0
0
0
12
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
12
0
12
0
0
0
0
12
0
12
34
12
% K
% Leu:
0
0
0
0
0
45
0
0
0
12
0
0
0
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
12
0
0
0
0
0
0
12
0
% N
% Pro:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
12
0
0
12
0
0
0
12
0
45
12
12
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
56
0
0
0
12
56
67
0
56
45
56
12
0
% S
% Thr:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
12
% T
% Val:
0
12
0
0
0
0
12
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _